Albumin and mortality in upper gastrointestinal bleeding

Albúmina sérica Hemorragia gastrointestinal superior Mortalidad hospitalaria Estratificación de riesgo Escalada de Rockall

Authors

January 24, 2025

with mortality in UGIB patients is essential for optimizing clinical management and reducing complications. Objective: To assess the predictive value of serum albumin levels for in-hospital mortality in patients with UGIB. Methods: A prospective study was conducted on 91 patients diagnosed with UGIB. Data on demographics, clinical characteristics, and laboratory parameters were collected. Bivariate analyses were performed using Chi-square, Student’s t-test, and Mann-Whitney U test. Significant variables were included in a multivariate logistic regression model to identify independent predictors of mortality. Results: Of the 91 patients, 65.9% were male, with a mean age of 67 ± 15.76 years. Hypoalbuminemia (2.3 g/dL) was significantly associated with mortality in the bivariate analysis (p = 0.01). However, serum albumin did not emerge as an independent predictor in the multivariate analysis (p = 0.257). Independent predictors included the Rockall score (p = 0.011) and length of hospital stay (p = 0.01). Discussion: Although hypoalbuminemia was associated with increased mortality in the bivariate analysis, it was not an independent predictor after adjusting for other clinical variables. The Rockall score and prolonged hospitalization were more robust predictors of mortality, emphasizing the need for multifactorial risk stratification in UGIB patients.